Supplement stacks / Carbamazepine + St Johns Wort
Can You Take Carbamazepine with St Johns Wort?
Carbamazepine and St Johns Wort: one interaction flagged, scored 3/10 (high risk). The count and score come from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice.
Safety at a glance
This score comes from an AI-written analysis of the pair. Our interaction rules check it and can only make it stricter, never milder. Informational only: it can't account for your medications, conditions, or genetics.
What the AI-written analysis says
Taking St. John's Wort with Carbamazepine can lead to significant interactions, as St. John's Wort is known to induce cytochrome P450 enzymes, potentially reducing the effectiveness of Carbamazepine. This combination should be approached with caution and under the guidance of a healthcare provider.
Carbamazepine is a prescription medication. This page describes publicly documented interactions — it can't see your dose, your other prescriptions, or your labs. Discuss any supplement with the prescriber or pharmacist who manages this medication before combining.
Known interactions
St. John's Wort may decrease the plasma concentration of Carbamazepine, leading to reduced therapeutic effects.
Carbamazepine
From the AI-written analysis.
Effective for seizure control and mood stabilization; requires monitoring for side effects and drug interactions.
Typical dosage: As prescribed or as directed on the label
- Dizziness
- Drowsiness
- Nausea
- Rash
- Regular blood tests may be needed to monitor levels and liver function.
- Risk of serious skin reactions.
St John's Wort
From the AI-written analysis.
Generally considered safe for short-term use; however, it can interact with many medications.
Typical dosage: 300-900 mg daily, divided into doses.
- Gastrointestinal upset
- Fatigue
- Allergic skin reactions
- Consult healthcare provider before use, especially with other medications.
- May cause photosensitivity.
Timing
No timing arrangement makes this combination safe — see the warnings above.
Watch out for
- Avoid combining St. John's Wort with Carbamazepine without medical supervision. Consult your healthcare provider for alternative treatments.
Frequently asked questions
Can you take Carbamazepine and St Johns Wort together?
Carbamazepine and St Johns Wort: one interaction flagged, scored 3/10 (high risk). The count and score come from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice.
What score does the Carbamazepine and St Johns Wort combination get?
The Carbamazepine and St Johns Wort combination is scored 3/10 (high risk). The score comes from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice. Always confirm with a healthcare professional.
When should you take Carbamazepine and St Johns Wort?
No timing arrangement makes this combination safe — see the warnings above.
What should you watch out for when combining Carbamazepine and St Johns Wort?
Avoid combining St. John's Wort with Carbamazepine without medical supervision. Consult your healthcare provider for alternative treatments.
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Not medical advice
AI-written analysis generated August 11, 2026, checked by our interaction rules · How our analysis works