Supplement stacks / Black Cohosh + St Johns Wort
Can You Take Black Cohosh with St Johns Wort?
Black Cohosh and St. John's Wort are both herbal supplements commonly used for different purposes, but their interactions are not well-studied. Caution is advised when taking them together due to potential unknown interactions. Consultation with a healthcare provider is recommended.
Conservative, AI-assisted reading of publicly available medical sources (NIH, Mayo Clinic, WebMD, Examine.com). Informational only — it can't account for your medications, conditions, or genetics.
Generally well-tolerated, but long-term safety is not well established; potential liver toxicity in rare cases.
Typical dosage: 40-80 mg daily.
- Stomach upset
- Headache
- Rash
- Consult healthcare provider if you have liver issues.
- Not recommended for use during pregnancy.
Generally considered safe for short-term use; however, it can interact with various medications, including antidepressants and birth control.
Typical dosage: 300-900 mg daily, divided into doses.
- Gastrointestinal upset
- Fatigue
- Allergic skin reactions
- May cause photosensitivity; use sunscreen.
- Consult healthcare provider if taking other medications.
Consider taking St. John's Wort in the morning and Black Cohosh in the evening to minimize potential interactions.
- Consult a healthcare provider before combining these supplements due to potential unknown interactions.
Can you take Black Cohosh and St Johns Wort together?
Black Cohosh and St. John's Wort are both herbal supplements commonly used for different purposes, but their interactions are not well-studied. Caution is advised when taking them together due to potential unknown interactions. Consultation with a healthcare provider is recommended.
How safe is the Black Cohosh and St Johns Wort combination?
Our analysis of publicly available medical sources scores this combination 5/10 (medium risk). This is an informational estimate, not medical advice — always confirm with a healthcare professional.
When should you take Black Cohosh and St Johns Wort?
Consider taking St. John's Wort in the morning and Black Cohosh in the evening to minimize potential interactions.
What should you watch out for when combining Black Cohosh and St Johns Wort?
Consult a healthcare provider before combining these supplements due to potential unknown interactions.
Taking more than these two? Run your complete supplement list — plus any medications — through the live checker for a combined analysis.
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Analysis generated August 11, 2026 · Sources include NIH, Mayo Clinic, WebMD, and Examine.com · How our analysis works