Supplement Science Blog
Evidence-based, source-cited articles on supplement interactions, timing, and how your genetics change what works for you.
Drugs.com app users report a steep new price — but the website checker is still free. What to look for in an interaction checker, and honest alternatives.
Leaving Medisafe after the free-plan changes? Honest alternatives for supplement users — MyTherapy for free reminders, Dosecast, and free interaction checks.
Ashwagandha with SSRIs like sertraline or Lexapro: low direct-interaction evidence, but watch for sedation, thyroid effects, and theoretical serotonin risks.
Calcium, iron, and magnesium can block levothyroxine (Synthroid) absorption. Here's how the spacing works, why timing matters for absorption, and how to protect your labs.
Magnesium and blood pressure meds like lisinopril or amlodipine are usually fine and sometimes helpful. Here's the real nuance on timing and additive effects.
St. John's wort has two real interaction mechanisms — it weakens many prescription drugs and stacks serotonin. Here are the combinations that actually matter.
Can you take turmeric with warfarin or blood thinners? Culinary amounts are low risk; high-dose curcumin supplements can raise bleeding risk. Here's what to do.
How the COMT warrior/worrier gene (Val158Met, rs4680) shapes your response to caffeine, L-theanine, tyrosine, and rhodiola, with honest caveats.
MTHFR C677T and A1298C variants explained: the folate cycle, methylfolate vs folic acid evidence, B12 and riboflavin, homocysteine, and who should test.
How to read raw 23andMe/Ancestry DNA for supplement insights: what's in the file, downloading it in 2026, the key nutrition SNPs, and the privacy risks.
Eight supplement pairs sorted by real severity — from mild issues like calcium and iron to serious risks like 5-HTP with antidepressants.
Vitamin D3 and K2 are sold as a must-take pair. Here's the real science, what trials prove, MK-4 vs MK-7, dosing, and the warfarin warning.
What the evidence really says about creatine: strength and cognition data, the kidney and hair-loss myths, loading vs 3-5g daily, caffeine, and women.
Which supplements genuinely need careful timing — iron, fat-soluble vitamins, melatonin — and which don't. A plain-language, evidence-based guide.
Comparing magnesium glycinate, citrate, oxide, malate, L-threonate and taurate on absorption, elemental content, GI effects, evidence, and drug interactions.