Supplement Science Blog
Evidence-based, source-cited articles on supplement interactions, timing, and how your genetics change what works for you.
MTHFR C677T and A1298C variants explained: the folate cycle, methylfolate vs folic acid evidence, B12 and riboflavin, homocysteine, and who should test.
How the COMT warrior/worrier gene (Val158Met, rs4680) shapes your response to caffeine, L-theanine, tyrosine, and rhodiola, with honest caveats.
How to read raw 23andMe/Ancestry DNA for supplement insights: what's in the file, downloading it in 2026, the key nutrition SNPs, and the privacy risks.
Vitamin D3 and K2 are sold as a must-take pair. Here's the real science, what trials prove, MK-4 vs MK-7, dosing, and the warfarin warning.
Comparing magnesium glycinate, citrate, oxide, malate, L-threonate and taurate on absorption, elemental content, GI effects, evidence, and drug interactions.
Which supplements genuinely need careful timing — iron, fat-soluble vitamins, melatonin — and which don't. A plain-language, evidence-based guide.
Eight supplement pairs sorted by real severity — from mild issues like calcium and iron to serious risks like 5-HTP with antidepressants.
What the evidence really says about creatine: strength and cognition data, the kidney and hair-loss myths, loading vs 3-5g daily, caffeine, and women.