How CanIStackThis Works

Learn how we analyze supplement information from medical websites to provide informational safety insights. Our system is designed to be transparent about its limitations and data sources.

1. Web Data Collection

We collect publicly available information about supplements from reputable medical websites, not proprietary databases or clinical trial data.

2. AI Analysis

Our AI system analyzes the collected information using conservative logic, with a bias toward safety and professional consultation for supplement combinations.

3. Informational Report

Receive informational insights with clear disclaimers about data limitations, confidence levels, and the importance of consulting healthcare professionals.

Our Data Sources

Medical Websites We Analyze

  • NIH Office of Dietary Supplements

    Government-published supplement fact sheets and safety information

  • WebMD

    Publicly available supplement information and drug interaction data

  • Mayo Clinic

    Consumer health information and supplement safety guidelines

  • Examine.com

    Evidence-based supplement research summaries and interaction data

Data Limitations

Website Information Only

We do not have access to proprietary medical databases, clinical trial data, or official FDA APIs.

Public Information

Our data comes from publicly available website content, not internal medical systems.

Conservative Approach

Due to data limitations, our system uses conservative logic that often recommends professional consultation.

Not Medical Advice

Our system provides informational insights only and should never replace professional medical guidance.

How Safety Scores Are Calculated

The deterministic safety net (not just AI)

Unlike black-box scores, the dangerous cases here are NOT left to AI judgment. A fixed, hand-written rule set runs on every analysis and can only make scores stricter — never more lenient. If your stack trips one of these, the score is floored to high-risk no matter what the AI thought:

  • • Two or more serotonergic agents (serotonin-syndrome risk)
  • • Two or more CNS depressants (phenibut, kratom, kava, benzos, opioids…)
  • • Multiple liver-stressing compounds (cleanse-stack herbs, SARMs, kava…)
  • • Blood thinners + bleeding-risk supplements
  • • Potassium + ACE inhibitors / potassium-sparing diuretics
  • • MAOIs + stimulants; stacked stimulants
  • • Statins + red yeast rice; lithium; thyroid/antibiotic mineral timing
  • • Upper-limit overlap tally (zinc, B6, vitamin A… across products)

The same transparency applies to spacing and pairing guidance: those come from published absorption data (NIH Office of Dietary Supplements), and where evidence is mixed — like calcium and zinc — we say so instead of overclaiming. We don't sell supplements, run ads, or take affiliate commissions, so nothing in the score is influenced by what anyone is selling.

Scoring Logic

High Scores (8-10)

Well-documented safe combinations from multiple reliable sources

Good Scores (6-7)

Generally regarded as safe with minor considerations noted

Moderate Scores (4-5)

Limited data available OR potential interactions identified

Low Scores (1-3)

Multiple sources suggest caution or clear warnings found

Conservative Bias

Our system tends to score combinations conservatively. More supplements generally lead to lower scores due to increased complexity and potential for interactions.

Risk Categories

Low Risk (8-10)8+

Well-documented safety profile with minimal concerns

Medium Risk (4-7)4-7

Some considerations noted, monitor use carefully

High Risk (1-3)1-3

Significant concerns identified, professional consultation recommended

Confidence Levels

All scores include confidence indicators based on the quality and quantity of available information from our data sources.

Our AI Analysis Approach

Text Analysis

Analyzes publicly available text from medical websites to identify potential concerns and safety information.

Conservative Logic

Uses conservative reasoning that prioritizes safety and frequently recommends professional consultation for supplement combinations.

Transparency

Provides clear disclaimers about data limitations, confidence levels, and the informational nature of all results.

Understanding System Limitations

What We Don't Have Access To

Direct access to PubMed or clinical trial databases
Official FDA or regulatory agency APIs
Proprietary medical or pharmaceutical databases
Real-time updates from clinical research

Important Disclaimers

Not Medical Advice

All results are informational only and should never replace professional medical consultation

Conservative Approach

Our system intentionally errs on the side of caution due to data limitations

Data Freshness

Information is collected from public websites and may not reflect the latest research

Individual Variation

Everyone responds differently — a free account can save your conditions and medications so checks account for them, and DNA analysis (Premium) adds genetic context, but no tool replaces individualized professional advice

Beyond the Checker

The interaction checker is the core of the site, but a few other tools build on the same data and rules:

  • Build My Stack (free) — answer a few questions about your goals and get a draft stack, interaction-checked before you see it. Includes a condition mode with GLP-1 companion checks (Ozempic, Mounjaro, Rybelsus — incl. Rybelsus absorption cautions).

  • Label tally (free) — adds up the real milligrams across your product labels using the NIH label database.

  • DNA report — gene-based supplement notes from your raw DNA file, with Premium or as a one-time $29 report.

  • Food & Absorption (Premium) — meals sequenced so your supplements absorb, built around your stack's timing and pairing guidance.

  • Timing schedules (Premium) — a daily when-to-take-what schedule based on published absorption data.

  • Advanced safety (Premium) — deeper checks that weigh interaction severity against your saved health conditions.

  • Phone reminders (free with an account) — push notifications for each dose, with training-day scheduling and calendar export.

Ready to Analyze Your Supplements?

Use our web-based analysis system to get informational insights about your supplement combinations. Remember: always consult with healthcare professionals before making supplement decisions.

Reminder: Our system provides informational insights only and should never replace professional medical advice.
Get Informational Analysis