Supplement stacks / Licorice Root + Lisinopril
Can You Take Licorice Root with Lisinopril?
Licorice Root and Lisinopril: one interaction flagged, scored 4/10 (high risk). The count and score come from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice.
Safety at a glance
High riskThis score comes from an AI-written analysis of the pair. Our interaction rules check it and can only make it stricter, never milder. Informational only: it can't account for your medications, conditions, or genetics.
What the AI-written analysis says
Licorice root may increase blood pressure and potassium levels, which can counteract the effects of lisinopril, a medication used to lower blood pressure. Caution is advised when combining these substances.
Lisinopril is a prescription medication. This page describes publicly documented interactions — it can't see your dose, your other prescriptions, or your labs. Discuss any supplement with the prescriber or pharmacist who manages this medication before combining.
Known interactions
Licorice root can lead to increased blood pressure and decreased effectiveness of lisinopril; monitor blood pressure closely and consult your healthcare provider.
Licorice Root
From the AI-written analysis.
May cause hypertension and hypokalemia, especially in high doses or prolonged use.
Typical dosage: Typically 200-400 mg per day.
- Hypertension
- Hypokalemia
- Headaches
- Consult healthcare provider if taking blood pressure medications.
- Avoid high doses for extended periods.
Lisinopril
From the AI-written analysis.
Generally well-tolerated but may cause dizziness, cough, or elevated potassium levels.
Typical dosage: As prescribed or as directed on the label
- Dizziness
- Cough
- Elevated potassium levels
- Monitor blood pressure regularly.
- Consult healthcare provider if experiencing side effects.
Timing
No timing arrangement makes this combination safe — see the warnings above.
Watch out for
- Real licorice (not DGL), especially in large amounts, can raise blood pressure and may make blood-pressure medicines work less well. Ask the prescriber or pharmacist before taking licorice with a medicine that lowers blood pressure, keep an eye on your blood pressure, and do not stop or change the prescription on your own.
- Monitor blood pressure closely when taking licorice root with lisinopril; consult your healthcare provider for personalized advice.
Frequently asked questions
Can you take Licorice Root and Lisinopril together?
Licorice Root and Lisinopril: one interaction flagged, scored 4/10 (high risk). The count and score come from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice.
What score does the Licorice Root and Lisinopril combination get?
The Licorice Root and Lisinopril combination is scored 4/10 (high risk). The score comes from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice. Always confirm with a healthcare professional.
When should you take Licorice Root and Lisinopril?
No timing arrangement makes this combination safe — see the warnings above.
What should you watch out for when combining Licorice Root and Lisinopril?
Real licorice (not DGL), especially in large amounts, can raise blood pressure and may make blood-pressure medicines work less well. Ask the prescriber or pharmacist before taking licorice with a medicine that lowers blood pressure, keep an eye on your blood pressure, and do not stop or change the prescription on your own. Monitor blood pressure closely when taking licorice root with lisinopril; consult your healthcare provider for personalized advice.
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Not medical advice
This analysis is based on general supplement information. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult qualified healthcare providers before starting any supplement regimen.
AI-written analysis generated September 2, 2026, checked by our interaction rules · How our analysis works