Supplement stacks / Diltiazem + St Johns Wort
Can You Take Diltiazem with St Johns Wort?
Diltiazem and St Johns Wort: one interaction flagged, scored 4/10 (medium risk). The count and score come from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice.
Safety at a glance
This score comes from an AI-written analysis of the pair. Our interaction rules check it and can only make it stricter, never milder. Informational only: it can't account for your medications, conditions, or genetics.
What the AI-written analysis says
St. John's Wort may interact with diltiazem, potentially affecting its efficacy due to enzyme induction. Caution is advised, and consultation with a healthcare provider is essential before combining these substances.
Diltiazem is a prescription medication. This page describes publicly documented interactions — it can't see your dose, your other prescriptions, or your labs. Discuss any supplement with the prescriber or pharmacist who manages this medication before combining.
Known interactions
Suggestion: Consult healthcare provider before use.
Diltiazem
From the AI-written analysis.
Generally well-tolerated; monitor for side effects, especially in combination with other medications.
Typical dosage: As prescribed or as directed on the label
- Dizziness
- Headache
- Edema
- Monitor blood pressure and heart rate; consult healthcare provider for any unusual symptoms.
St. John's Wort
From the AI-written analysis.
Generally safe for most individuals; however, it can interact with various medications.
Typical dosage: 300-900 mg daily, divided into doses
- Gastrointestinal upset
- Fatigue
- Allergic skin reactions
- May reduce the effectiveness of certain medications, including diltiazem; consult healthcare provider before use.
Timing
Take as prescribed — we do not schedule prescription medications. Follow the label or your prescriber, and ask your pharmacist before changing when you take it.
Recommendations
- Avoid combining St. John's Wort with diltiazem without medical supervision.
Watch out for
- Consult healthcare provider before starting St. John's Wort while on diltiazem.
Frequently asked questions
Can you take Diltiazem and St Johns Wort together?
Diltiazem and St Johns Wort: one interaction flagged, scored 4/10 (medium risk). The count and score come from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice.
What score does the Diltiazem and St Johns Wort combination get?
The Diltiazem and St Johns Wort combination is scored 4/10 (medium risk). The score comes from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice. Always confirm with a healthcare professional.
When should you take Diltiazem and St Johns Wort?
Take as prescribed — we do not schedule prescription medications. Follow the label or your prescriber, and ask your pharmacist before changing when you take it.
What should you watch out for when combining Diltiazem and St Johns Wort?
Consult healthcare provider before starting St. John's Wort while on diltiazem.
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Not medical advice
AI-written analysis generated August 11, 2026, checked by our interaction rules · How our analysis works