Supplement stacks / Apixaban + Vitamin K

Can You Take Apixaban with Vitamin K?

Apixaban and Vitamin K: one interaction flagged, scored 4/10 (high risk). The count and score come from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice.

Safety at a glance

High risk
Safety score4/10

This score comes from an AI-written analysis of the pair. Our interaction rules check it and can only make it stricter, never milder. Informational only: it can't account for your medications, conditions, or genetics.

What the AI-written analysis says

Taking Apixaban with Vitamin K can pose risks due to Vitamin K's role in blood clotting, which may counteract the effects of Apixaban, an anticoagulant. Monitoring is essential to ensure safety.

Apixaban is a prescription medication. This page describes publicly documented interactions — it can't see your dose, your other prescriptions, or your labs. Discuss any supplement with the prescriber or pharmacist who manages this medication before combining.

Known interactions

Apixaban × Vitamin K
high risk

Vitamin K can reduce the effectiveness of Apixaban, potentially increasing the risk of clot formation. Regular monitoring of INR is recommended, and intake of Vitamin K should be consistent.

Apixaban

From the AI-written analysis.

Apixaban is generally well-tolerated but can increase the risk of bleeding. Regular monitoring is necessary, especially when combined with other substances affecting coagulation.

Typical dosage: As prescribed or as directed on the label

Common side effects:
  • Bleeding
  • Anemia
  • Nausea
Warnings:
  • Monitor for signs of bleeding; consult healthcare provider if any unusual bruising or bleeding occurs.

Vitamin K

From the AI-written analysis.

Vitamin K is generally safe but can interfere with anticoagulant medications like Apixaban. Consistency in intake is crucial.

Typical dosage: Varies by product — follow the label.

Common side effects:
  • Allergic reactions (rare)
  • Gastrointestinal upset (rare)
Warnings:
  • Consult healthcare provider before starting Vitamin K if on anticoagulants.

Timing

Take as prescribed — we do not schedule prescription medications. Follow the label or your prescriber, and ask your pharmacist before changing when you take it.

Watch out for

  • Regularly monitor INR levels and maintain consistent Vitamin K intake to avoid fluctuations in anticoagulant effectiveness.

Frequently asked questions

Can you take Apixaban and Vitamin K together?

Apixaban and Vitamin K: one interaction flagged, scored 4/10 (high risk). The count and score come from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice.

What score does the Apixaban and Vitamin K combination get?

The Apixaban and Vitamin K combination is scored 4/10 (high risk). The score comes from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice. Always confirm with a healthcare professional.

When should you take Apixaban and Vitamin K?

Take as prescribed — we do not schedule prescription medications. Follow the label or your prescriber, and ask your pharmacist before changing when you take it.

What should you watch out for when combining Apixaban and Vitamin K?

Regularly monitor INR levels and maintain consistent Vitamin K intake to avoid fluctuations in anticoagulant effectiveness.

Check your full stack

Taking more than these two? Add everything you take, medicines included, to your list. We check each supplement on your list against the rest of it, and name anything we could not check. Free, and you don’t need an account.

Analyze my stack

What your DNA adds

Some genes in a raw 23andMe or AncestryDNA file are linked to how the body handles nutrients. The DNA report says what yours are linked to and, where there is one, which blood test would tell you more.

See the DNA report

AI-written analysis generated August 28, 2026, checked by our interaction rules · How our analysis works