Supplement stacks / Magnesium + St Johns Wort
Can You Take Magnesium with St Johns Wort?
Magnesium and St Johns Wort: no interactions flagged, scored 7/10 (medium risk). The count and score come from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice.
Safety at a glance
This score comes from an AI-written analysis of the pair. Our interaction rules check it and can only make it stricter, never milder. Informational only: it can't account for your medications, conditions, or genetics.
What the AI-written analysis says
Magnesium and St. John's Wort can generally be taken together, but caution is advised due to potential interactions with other medications. Magnesium is known for its role in various bodily functions and can enhance vitamin D absorption. St. John's Wort is often used for mood support but has limited evidence regarding its efficacy and safety profile. Users should consult healthcare providers, especially if they are on other medications.
Magnesium
From the AI-written analysis.
Generally safe when taken within recommended dosages; caution in individuals with kidney disease.
Typical dosage: 200-400 mg daily
- Diarrhea
- Nausea
- Abdominal cramping
- Avoid in individuals with kidney disease; consult healthcare provider if on other medications.
St John's Wort
From the AI-written analysis.
Generally safe for short-term use; may cause photosensitivity and interact with various medications.
Typical dosage: Follow manufacturer guidelines
- Dry mouth
- Dizziness
- Fatigue
- Consult healthcare provider if taking antidepressants or other medications; may reduce effectiveness of certain drugs.
Also commonly mentioned
These come up in questions about this combination. They are not part of the pair above. From the AI-written analysis.
Vitamin D
Safe when taken within recommended dosages; important for calcium absorption.
Typical dosage: 600-800 IU daily
- Nausea
- Vomiting
- Weakness
- Monitor calcium levels if taking high doses; consult healthcare provider if on other medications.
Calcium
Generally safe; excessive intake can lead to kidney stones.
Typical dosage: 1000-1200 mg daily
- Constipation
- Gas
- Bloating
- Avoid excessive intake; consult healthcare provider if on other medications.
Omega-3 Fatty Acids
Generally safe; may interact with anticoagulants.
Typical dosage: 1000-3000 mg daily
- Fishy aftertaste
- Nausea
- Diarrhea
- Monitor bleeding risk if on anticoagulants; consult healthcare provider.
Timing
Magnesium can be taken at any time, but may be best absorbed with food. St. John's Wort should be taken consistently at the same time each day for optimal effect.
Watch out for
- Consult healthcare provider before starting St. John's Wort if taking other medications due to potential interactions.
Frequently asked questions
Can you take Magnesium and St Johns Wort together?
Magnesium and St Johns Wort: no interactions flagged, scored 7/10 (medium risk). The count and score come from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice.
What score does the Magnesium and St Johns Wort combination get?
The Magnesium and St Johns Wort combination is scored 7/10 (medium risk). The score comes from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice. Always confirm with a healthcare professional.
When should you take Magnesium and St Johns Wort?
Magnesium can be taken at any time, but may be best absorbed with food. St. John's Wort should be taken consistently at the same time each day for optimal effect.
What should you watch out for when combining Magnesium and St Johns Wort?
Consult healthcare provider before starting St. John's Wort if taking other medications due to potential interactions.
Check your full stack
Taking more than these two? Add everything you take, medicines included, to your list. We check each supplement on your list against the rest of it, and name anything we could not check. Free, and you don’t need an account.
Analyze my stackWhat your DNA adds
Some genes in a raw 23andMe or AncestryDNA file are linked to how the body handles nutrients. The DNA report says what yours are linked to and, where there is one, which blood test would tell you more.
See the DNA reportRelated combinations
Not medical advice
AI-written analysis generated August 11, 2026, checked by our interaction rules · How our analysis works