Supplement stacks / Magnesium + Rosuvastatin

Can You Take Magnesium with Rosuvastatin?

Taking magnesium with rosuvastatin is generally considered safe, but caution is advised due to potential interactions affecting absorption and efficacy. Monitoring kidney function is important when using magnesium, especially in conjunction with statins.

Safety at a glance
High risk
Safety score4/10

Conservative, AI-assisted reading of publicly available medical sources (NIH, Mayo Clinic, WebMD, Examine.com). Informational only — it can't account for your medications, conditions, or genetics.

Known interactions
Magnesium × Rosuvastatin
medium

Magnesium may interfere with the absorption of rosuvastatin; it is advisable to separate the intake of these substances by at least 2 hours.

Magnesium

Generally safe for most individuals; caution in those with kidney disease as it can lead to toxicity.

Typical dosage: 200-400 mg daily

Common side effects:
  • Diarrhea
  • Nausea
  • Abdominal cramping
Warnings:
  • Use with caution if you have kidney disease; consult a healthcare provider before starting supplementation.
Rosuvastatin

Generally well-tolerated; monitor for muscle pain or weakness, which may indicate rhabdomyolysis.

Typical dosage: Follow manufacturer guidelines; typically 5-40 mg daily

Common side effects:
  • Muscle pain
  • Headache
  • Nausea
Warnings:
  • Consult a healthcare provider for potential interactions with supplements and other medications.
Timing

Take magnesium at least 2 hours apart from rosuvastatin to minimize absorption interference.

Watch out for
  • Monitor for any signs of muscle pain or weakness while taking rosuvastatin, especially if magnesium is also being taken.
Frequently asked questions

Can you take Magnesium and Rosuvastatin together?

Taking magnesium with rosuvastatin is generally considered safe, but caution is advised due to potential interactions affecting absorption and efficacy. Monitoring kidney function is important when using magnesium, especially in conjunction with statins.

How safe is the Magnesium and Rosuvastatin combination?

Our analysis of publicly available medical sources scores this combination 4/10 (high risk). This is an informational estimate, not medical advice — always confirm with a healthcare professional.

When should you take Magnesium and Rosuvastatin?

Take magnesium at least 2 hours apart from rosuvastatin to minimize absorption interference.

What should you watch out for when combining Magnesium and Rosuvastatin?

Monitor for any signs of muscle pain or weakness while taking rosuvastatin, especially if magnesium is also being taken.

Check your full stack

Taking more than these two? Run your complete supplement list — plus any medications — through the live checker for a combined analysis.

Analyze my stack
Personalize it with your DNA

Genetics change how you process supplements like these. Upload raw 23andMe or Ancestry data for a personalized supplement report.

See the DNA report

Analysis generated August 28, 2026 · Sources include NIH, Mayo Clinic, WebMD, and Examine.com · How our analysis works