Supplement stacks / Levetiracetam + Magnesium

Can You Take Levetiracetam with Magnesium?

Levetiracetam is an anticonvulsant medication, while magnesium is a mineral supplement commonly used for various health benefits. There are no direct contraindications between levetiracetam and magnesium, but caution is advised due to potential effects on absorption and individual health conditions.

Safety at a glance
Medium risk
Safety score7/10

Conservative, AI-assisted reading of publicly available medical sources (NIH, Mayo Clinic, WebMD, Examine.com). Informational only — it can't account for your medications, conditions, or genetics.

Known interactions
Levetiracetam × Magnesium
medium

Magnesium may affect the absorption of levetiracetam; it is advisable to space the intake of these substances by at least 2 hours to minimize potential interaction.

Levetiracetam

Generally well-tolerated, but may cause side effects such as dizziness, fatigue, and mood changes. Monitor for any unusual symptoms.

Typical dosage: Follow manufacturer guidelines; typically starts at 500 mg twice daily.

Common side effects:
  • Dizziness
  • Fatigue
  • Mood changes
  • Nausea
Warnings:
  • Consult healthcare provider for any unusual side effects or if you have kidney issues.
Magnesium

Generally safe for most people; however, those with kidney disease should avoid high doses.

Typical dosage: 200-400 mg daily.

Common side effects:
  • Diarrhea
  • Nausea
  • Abdominal cramping
Warnings:
  • Avoid high doses if you have kidney disease; consult a healthcare provider if unsure.
Timing

Take magnesium at least 2 hours apart from levetiracetam to minimize potential absorption issues.

Watch out for
  • Monitor for any unusual symptoms when combining levetiracetam and magnesium; consult your healthcare provider if you experience significant side effects.
Frequently asked questions

Can you take Levetiracetam and Magnesium together?

Levetiracetam is an anticonvulsant medication, while magnesium is a mineral supplement commonly used for various health benefits. There are no direct contraindications between levetiracetam and magnesium, but caution is advised due to potential effects on absorption and individual health conditions.

How safe is the Levetiracetam and Magnesium combination?

Our analysis of publicly available medical sources scores this combination 7/10 (medium risk). This is an informational estimate, not medical advice — always confirm with a healthcare professional.

When should you take Levetiracetam and Magnesium?

Take magnesium at least 2 hours apart from levetiracetam to minimize potential absorption issues.

What should you watch out for when combining Levetiracetam and Magnesium?

Monitor for any unusual symptoms when combining levetiracetam and magnesium; consult your healthcare provider if you experience significant side effects.

Check your full stack

Taking more than these two? Run your complete supplement list — plus any medications — through the live checker for a combined analysis.

Analyze my stack
Personalize it with your DNA

Genetics change how you process supplements like these. Upload raw 23andMe or Ancestry data for a personalized supplement report.

See the DNA report

Analysis generated August 28, 2026 · Sources include NIH, Mayo Clinic, WebMD, and Examine.com · How our analysis works