Supplement stacks / Codeine + Magnesium
Can You Take Codeine with Magnesium?
Codeine and Magnesium: one interaction flagged, scored 6/10 (medium risk). The count and score come from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice.
Safety at a glance
This score comes from an AI-written analysis of the pair. Our interaction rules check it and can only make it stricter, never milder. Informational only: it can't account for your medications, conditions, or genetics.
What the AI-written analysis says
Taking codeine and magnesium together may pose some risks, particularly related to the potential for magnesium to affect the absorption of codeine. While magnesium is generally safe at typical dosages, caution is advised due to the limited evidence on codeine's interactions and its potential side effects.
Codeine is a prescription medication. This page describes publicly documented interactions — it can't see your dose, your other prescriptions, or your labs. Discuss any supplement with the prescriber or pharmacist who manages this medication before combining.
Known interactions
Magnesium may affect the absorption of codeine, potentially leading to reduced effectiveness. It is advisable to separate the intake of these substances by at least 2 hours.
Codeine
From the AI-written analysis.
Use with caution, especially in individuals with respiratory issues or a history of substance abuse. Monitor for signs of dependence.
Typical dosage: As prescribed or as directed on the label
- Drowsiness
- Constipation
- Nausea
- Consult healthcare provider if you have respiratory issues or a history of substance abuse.
- Use caution when driving or operating machinery.
Magnesium
From the AI-written analysis.
Generally safe at typical dosages; caution in individuals with kidney disease.
Typical dosage: 200-400 mg daily.
- Diarrhea
- Nausea
- Abdominal cramping
- Consult healthcare provider if you have kidney disease.
- Excessive intake may lead to magnesium toxicity.
Timing
Take as prescribed — we do not schedule prescription medications. Follow the label or your prescriber, and ask your pharmacist before changing when you take it.
Frequently asked questions
Can you take Codeine and Magnesium together?
Codeine and Magnesium: one interaction flagged, scored 6/10 (medium risk). The count and score come from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice.
What score does the Codeine and Magnesium combination get?
The Codeine and Magnesium combination is scored 6/10 (medium risk). The score comes from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice. Always confirm with a healthcare professional.
When should you take Codeine and Magnesium?
Take as prescribed — we do not schedule prescription medications. Follow the label or your prescriber, and ask your pharmacist before changing when you take it.
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Not medical advice
AI-written analysis generated August 28, 2026, checked by our interaction rules · How our analysis works