Supplement stacks / Calcium + Omeprazole
Can You Take Calcium with Omeprazole?
Calcium and Omeprazole: one interaction flagged, scored 6/10 (medium risk). The count and score come from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice.
Safety at a glance
This score comes from an AI-written analysis of the pair. Our interaction rules check it and can only make it stricter, never milder. Informational only: it can't account for your medications, conditions, or genetics.
What the AI-written analysis says
Calcium and omeprazole can be taken together, but caution is advised due to potential interactions affecting calcium absorption. Omeprazole may reduce stomach acidity, which can impair calcium absorption, particularly from calcium carbonate supplements. It is recommended to separate the intake of these substances to mitigate risks.
Omeprazole is a prescription medication. This page describes publicly documented interactions — it can't see your dose, your other prescriptions, or your labs. Discuss any supplement with the prescriber or pharmacist who manages this medication before combining.
Known interactions
Omeprazole may reduce stomach acidity, which can impair the absorption of calcium, particularly from calcium carbonate. It is advisable to separate the intake of calcium and omeprazole by at least 2 hours.
Calcium
From the AI-written analysis.
Generally safe when taken as directed; however, excessive intake can lead to hypercalcemia and kidney stones. Consult a healthcare provider if you have kidney issues or are on certain medications.
Typical dosage: Varies by product — follow the label.
- Constipation
- Nausea
- Stomach upset
- Consult a healthcare provider if you have a history of kidney stones or hypercalcemia.
Omeprazole
From the AI-written analysis.
Generally safe when taken as prescribed; long-term use may lead to vitamin B12 deficiency and increased risk of fractures. Consult a healthcare provider for prolonged use.
Typical dosage: As prescribed or as directed on the label
- Headache
- Diarrhea
- Nausea
- Long-term use may require monitoring for vitamin B12 levels.
Timing
Take as prescribed — we do not schedule prescription medications. Follow the label or your prescriber, and ask your pharmacist before changing when you take it.
Frequently asked questions
Can you take Calcium and Omeprazole together?
Calcium and Omeprazole: one interaction flagged, scored 6/10 (medium risk). The count and score come from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice.
What score does the Calcium and Omeprazole combination get?
The Calcium and Omeprazole combination is scored 6/10 (medium risk). The score comes from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice. Always confirm with a healthcare professional.
When should you take Calcium and Omeprazole?
Take as prescribed — we do not schedule prescription medications. Follow the label or your prescriber, and ask your pharmacist before changing when you take it.
Check your full stack
Taking more than these two? Add everything you take, medicines included, to your list. We check each supplement on your list against the rest of it, and name anything we could not check. Free, and you don’t need an account.
Analyze my stackWhat your DNA adds
Some genes in a raw 23andMe or AncestryDNA file are linked to how the body handles nutrients. The DNA report says what yours are linked to and, where there is one, which blood test would tell you more.
See the DNA reportRelated combinations
Not medical advice
AI-written analysis generated August 28, 2026, checked by our interaction rules · How our analysis works