Supplement stacks / Calcium + Digoxin

Can You Take Calcium with Digoxin?

Calcium and Digoxin: one interaction flagged, scored 5/10 (medium risk). The count and score come from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice.

Safety at a glance

Medium risk
Safety score5/10

This score comes from an AI-written analysis of the pair. Our interaction rules check it and can only make it stricter, never milder. Informational only: it can't account for your medications, conditions, or genetics.

What the AI-written analysis says

Taking calcium with digoxin can lead to potential interactions that may affect the absorption and efficacy of digoxin. While both substances are commonly used, caution is advised due to the risk of altered digoxin levels in the body. It is essential to consult a healthcare provider before combining these substances.

Digoxin is a prescription medication. This page describes publicly documented interactions — it can't see your dose, your other prescriptions, or your labs. Discuss any supplement with the prescriber or pharmacist who manages this medication before combining.

Known interactions

Calcium × Digoxin
medium risk

Calcium can interfere with the absorption of digoxin, potentially leading to decreased effectiveness of the medication. It is recommended to separate the intake of calcium and digoxin by at least 2 hours.

Calcium

From the AI-written analysis.

Calcium is generally safe when taken at recommended dosages, but excessive intake can lead to hypercalcemia and other complications. Consult a healthcare provider if you have kidney issues or are on certain medications.

Typical dosage: Varies by product — follow the label.

Common side effects:
  • Constipation
  • Nausea
  • Stomach upset
Warnings:
  • Consult a healthcare provider if you have kidney disease or are taking medications that affect calcium levels.

Digoxin

From the AI-written analysis.

Digoxin has a narrow therapeutic index, meaning that the difference between an effective dose and a toxic dose is small. Regular monitoring of blood levels is essential.

Typical dosage: As prescribed or as directed on the label

Common side effects:
  • Nausea
  • Vomiting
  • Dizziness
  • Visual disturbances
Warnings:
  • Monitor for signs of digoxin toxicity, especially if taking calcium or other medications that may affect heart rhythm.

Timing

Take as prescribed — we do not schedule prescription medications. Follow the label or your prescriber, and ask your pharmacist before changing when you take it.

Frequently asked questions

Can you take Calcium and Digoxin together?

Calcium and Digoxin: one interaction flagged, scored 5/10 (medium risk). The count and score come from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice.

What score does the Calcium and Digoxin combination get?

The Calcium and Digoxin combination is scored 5/10 (medium risk). The score comes from an AI-written analysis checked against our interaction rules, which can only make it stricter. Not medical advice. Always confirm with a healthcare professional.

When should you take Calcium and Digoxin?

Take as prescribed — we do not schedule prescription medications. Follow the label or your prescriber, and ask your pharmacist before changing when you take it.

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What your DNA adds

Some genes in a raw 23andMe or AncestryDNA file are linked to how the body handles nutrients. The DNA report says what yours are linked to and, where there is one, which blood test would tell you more.

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AI-written analysis generated August 28, 2026, checked by our interaction rules · How our analysis works